Evrysdi helped infants survive without permanent breathing support

Out of the infants taking Evrysdi

The infants in this part of the study ranged in age from 3 to 7 months at the start of treatment, but many were closer to 7 months. 

Additional exploratory observations in eating and swallowing

This information is considered exploratory. This means it was not designed to show a treatment effect so conclusions cannot be drawn from these observational data.

Out of the infants taking the recommended dose of Evrysdi for 12 months:

• 88% were able to eat by mouth (15 out of 17 infants)^†
• 88% were able to swallow (15 out of 17 infants)^‡

*Permanent support was defined as having a tracheostomy (a surgery where a tube is inserted in the front of the throat into the windpipe) or more than 21 days of noninvasive ventilation support (16 or more hours a day) or being intubated (a procedure where a breathing tube is inserted down the throat and into the windpipe) to help with breathing in the absence of an acute reversible event.
^†Two of these infants could eat some food by mouth, but also used a feeding tube.
^‡One infant could not swallow at the start of the study.